Epidural clonidine applied being an adjunct to neighborhood anesthetics has three different mechanisms of action. First, the stimulation of alpha-2-receptors while in the dorsal horn cuts down pain transmission. Next, clonidine can result in neighborhood vasoconstriction that limits vascular removal of local epidural anesthetics. Clonidine is a protracted-term medication. https://vannevarr592gey4.mysticwiki.com/user