Tramadol wasn't mutagenic in the following assays: Ames Salmonella microsomal activation take a look at, CHO/HPRT mammalian cell assay, mouse lymphoma assay (from the absence of metabolic activation), dominant lethal mutation tests in mice, chromosome aberration examination in Chinese hamsters, and bone marrow micronucleus tests in mice and Chinese hamsters. https://salvadoru009lxj2.thebindingwiki.com/user