Butabarbital will lessen the level or effect of zaleplon by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Insignificant/Importance Unfamiliar. butabarbital will decrease the level or impact of midazolam by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep an eye on. near You should validate that you want to to log out of Medscape. https://richardf691lqg4.wikiexpression.com/user